The Food and Drug Administration has indicated it would authorize a vaccine that's safe and at least 50% effective. The differences between the effectiveness of one or two doses highlights the importance of fully vaccinating adults, the researchers said. The vaccine, however, appeared to be less potent against other variants. A single dose of the vaccine provided 58% protection against infection, 76% against hospitalization and 77% against death, the investigators found. The company said Covaxin has shown signs of potential effectiveness against three variants of the coronavirus. The comparable proportions of polyclonal antibodies directed against the epitopes of the new variants are very similar in vaccine recipients and infected individuals. Pfizer Vaccine Shows Reduced Effectiveness Against COVID Variants, Israeli Study Shows. The effectiveness against the variants was lower than the 95% efficacy demonstrated in clinical trial data for which the Pfizer vaccine received emergency use … Israeli researchers found people who received two doses of the Pfizer vaccine and still got infected were eight times more likely to be infected with the South African variant compared to infected people who were unvaccinated. Pfizer vaccine holds its own against variants. Covaxin is India's COVID-19 vaccine, which Ocugen is …
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